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Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1
BACKGROUND: Psoriasis is a common inflammatory skin disease. Abnormal proliferation of keratinocytes is one of the psoriatic histopathological features. Indirubin has an essential effect on the proliferation and activation of keratinocytes; however, in psoriasis, the specific mechanism of action of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427955/ https://www.ncbi.nlm.nih.gov/pubmed/32795328 http://dx.doi.org/10.1186/s12906-020-03045-9 |