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Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism

Increased energy metabolism is responsible for supporting the abnormally upregulated proliferation and biosynthesis of cancer cells. The key cellular energy sensor AMP-activated protein kinase (AMPK) and the glycolytic enzyme alpha-enolase (α-enolase) have been identified as the targets for active c...

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Detalles Bibliográficos
Autores principales: Huang, Qi, Zhang, Hui, Bai, Li Ping, Law, Betty Yuen Kwan, Xiong, Haoming, Zhou, Xiaobo, Xiao, Riping, Qu, Yuan Qing, Mok, Simon Wing Fai, Liu, Liang, Wong, Vincent Kam Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427995/
https://www.ncbi.nlm.nih.gov/pubmed/32796841
http://dx.doi.org/10.1038/s41419-020-02881-4