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Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism
Increased energy metabolism is responsible for supporting the abnormally upregulated proliferation and biosynthesis of cancer cells. The key cellular energy sensor AMP-activated protein kinase (AMPK) and the glycolytic enzyme alpha-enolase (α-enolase) have been identified as the targets for active c...
Autores principales: | Huang, Qi, Zhang, Hui, Bai, Li Ping, Law, Betty Yuen Kwan, Xiong, Haoming, Zhou, Xiaobo, Xiao, Riping, Qu, Yuan Qing, Mok, Simon Wing Fai, Liu, Liang, Wong, Vincent Kam Wai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427995/ https://www.ncbi.nlm.nih.gov/pubmed/32796841 http://dx.doi.org/10.1038/s41419-020-02881-4 |
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