Kidney-based in vivo model for drug-induced nephrotoxicity testing

The need is critical and urgent for a real-time, highly specific, and sensitive acute kidney injury biomarker. This study sought to establish a sensitive and specific Miox-NanoLuc transgenic mouse for early detection of drug-induced nephrotoxicity. We generated Miox-NanoLuc transgenic mice with kidn...

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Detalles Bibliográficos
Autores principales: Chiou, Yuan-Yow, Jiang, Si-Tse, Ding, Yu-Sian, Cheng, Yu-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428004/
https://www.ncbi.nlm.nih.gov/pubmed/32796873
http://dx.doi.org/10.1038/s41598-020-70502-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428004/
https://www.ncbi.nlm.nih.gov/pubmed/32796873
http://dx.doi.org/10.1038/s41598-020-70502-3

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