Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant tau transgenic mice

Antibodies have been explored extensively as a potential therapeutic for Alzheimer’s disease, where amyloid-β (Aβ) peptides and the tau protein deposit in patient brains. While the major focus of antibody-based therapy development was on Aβ, arguably with limited success in clinical trials, targetin...

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Detalles Bibliográficos
Autores principales: van der Hoven, Julia, van Hummel, Annika, Przybyla, Magdalena, Asih, Prita R., Gajwani, Mehul, Feiten, Astrid F., Ke, Yazi D., Ittner, Arne, van Eersel, Janet, Ittner, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428012/
https://www.ncbi.nlm.nih.gov/pubmed/32796905
http://dx.doi.org/10.1038/s41598-020-70845-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428012/
https://www.ncbi.nlm.nih.gov/pubmed/32796905
http://dx.doi.org/10.1038/s41598-020-70845-x

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