Optical Control of Sphingosine-1-Phosphate Formation and Function

Sphingosine-1-phosphate (S1P) plays important roles as a signaling lipid in a variety of physiological and pathophysiological processes. S1P signals via a family of G protein-coupled receptors (S1P(1–5)) and intracellular targets. Here, we report on photoswitchable analogs of S1P and its precursor s...

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Detalles Bibliográficos
Autores principales: Morstein, Johannes, Hill, Rose Z., Novak, Alexander J. E., Feng, Suihan, Norman, Derek D., Donthamsetti, Prashant C., Frank, James A., Harayama, Takeshi, Williams, Benjamin M., Parrill, Abby L., Tigyi, Gabor J., Riezman, Howard, Isacoff, Ehud Y., Bautista, Diana M., Trauner, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428055/
https://www.ncbi.nlm.nih.gov/pubmed/31036923
http://dx.doi.org/10.1038/s41589-019-0269-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428055/
https://www.ncbi.nlm.nih.gov/pubmed/31036923
http://dx.doi.org/10.1038/s41589-019-0269-7

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