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Quantifying synergy in the bioassay-guided fractionation of natural product extracts

Mixtures of drugs often have greater therapeutic value than any of their constituent drugs alone, and such combination therapies are widely used to treat diseases such as cancer, malaria, and viral infections. However, developing useful drug mixtures is challenging due to complex interactions betwee...

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Detalles Bibliográficos
Autores principales: Dettweiler, Micah, Marquez, Lewis, Bao, Max, Quave, Cassandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428089/
https://www.ncbi.nlm.nih.gov/pubmed/32797045
http://dx.doi.org/10.1371/journal.pone.0235723