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Intracellular neutralisation of rotavirus by VP6-specific IgG

Rotavirus is a major cause of gastroenteritis in children, with infection typically inducing high levels of protective antibodies. Antibodies targeting the middle capsid protein VP6 are particularly abundant, and as VP6 is only exposed inside cells, neutralisation must be post-entry. However, while...

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Detalles Bibliográficos
Autores principales: Caddy, Sarah L., Vaysburd, Marina, Wing, Mark, Foss, Stian, Andersen, Jan Terje, O‘Connell, Kevin, Mayes, Keith, Higginson, Katie, Iturriza-Gómara, Miren, Desselberger, Ulrich, James, Leo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428215/
https://www.ncbi.nlm.nih.gov/pubmed/32750093
http://dx.doi.org/10.1371/journal.ppat.1008732