HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+) T cells

Seasonal influenza virus infections cause 290,000–650,000 deaths annually and severe morbidity in 3–5 million people. CD8(+) T-cell responses towards virus-derived peptide/human leukocyte antigen (HLA) complexes provide the broadest cross-reactive immunity against human influenza viruses. Several un...

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Detalles Bibliográficos
Autores principales: Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O., Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428290/
https://www.ncbi.nlm.nih.gov/pubmed/32750095
http://dx.doi.org/10.1371/journal.ppat.1008714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428290/
https://www.ncbi.nlm.nih.gov/pubmed/32750095
http://dx.doi.org/10.1371/journal.ppat.1008714

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