Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal cells supporting tumor progression, whose origin remains to be fully elucidated. Osterix (Osx) is a marker of osteogenic differentiation, expressed in skeletal progenitor stem cells and bone-forming osteoblasts. We re...

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Detalles Bibliográficos
Autores principales: Ricci, Biancamaria, Tycksen, Eric, Celik, Hamza, Belle, Jad I, Fontana, Francesca, Civitelli, Roberto, Faccio, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428306/
https://www.ncbi.nlm.nih.gov/pubmed/32755539
http://dx.doi.org/10.7554/eLife.54659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428306/
https://www.ncbi.nlm.nih.gov/pubmed/32755539
http://dx.doi.org/10.7554/eLife.54659

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