Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms—An intravital imaging study in mice

Extracellular polymeric substances (EPS) hold infectious biofilms together and limit antimicrobial penetration and clinical infection control. Here, we present zwitterionic micelles as a previously unexplored, synthetic self-targeting dispersant. First, a pH-responsive poly(ε-caprolactone)-block-pol...

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Detalles Bibliográficos
Autores principales: Tian, Shuang, Su, Linzhu, Liu, Yong, Cao, Jingjing, Yang, Guang, Ren, Yijin, Huang, Fan, Liu, Jianfeng, An, Yingli, van der Mei, Henny C., Busscher, Henk J., Shi, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428326/
https://www.ncbi.nlm.nih.gov/pubmed/32851173
http://dx.doi.org/10.1126/sciadv.abb1112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428326/
https://www.ncbi.nlm.nih.gov/pubmed/32851173
http://dx.doi.org/10.1126/sciadv.abb1112

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