Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease

Noncanonical functions of autophagy proteins have been implicated in neurodegenerative conditions, including Alzheimer’s disease (AD). The WD domain of the autophagy protein Atg16L is dispensable for canonical autophagy but required for its noncanonical functions. Two-year-old mice lacking this doma...

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Detalles Bibliográficos
Autores principales: Heckmann, Bradlee L., Teubner, Brett J. W., Boada-Romero, Emilio, Tummers, Bart, Guy, Clifford, Fitzgerald, Patrick, Mayer, Ulrike, Carding, Simon, Zakharenko, Stanislav S., Wileman, Thomas, Green, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428329/
https://www.ncbi.nlm.nih.gov/pubmed/32851186
http://dx.doi.org/10.1126/sciadv.abb9036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428329/
https://www.ncbi.nlm.nih.gov/pubmed/32851186
http://dx.doi.org/10.1126/sciadv.abb9036

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