Transcription and DNA Methylation Patterns of Blood-Derived CD8(+) T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis

BACKGROUND & AIMS: Gene expression patterns of CD8(+) T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed to validate these findings in independent patient cohorts. METHODS: We obtained peripheral blood samples from 112 childr...

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Detalles Bibliográficos
Autores principales: Gasparetto, Marco, Payne, Felicity, Nayak, Komal, Kraiczy, Judith, Glemas, Claire, Philip-McKenzie, Yosef, Ross, Alexander, Edgar, Rachel D., Zerbino, Daniel R., Salvestrini, Camilla, Torrente, Franco, Ventham, Nicholas T., Kalla, Rahul, Satsangi, Jack, Sarkies, Peter, Heuschkel, Robert, Zilbauer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: by the AGA Institute 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428744/
https://www.ncbi.nlm.nih.gov/pubmed/32814113
http://dx.doi.org/10.1053/j.gastro.2020.08.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428744/
https://www.ncbi.nlm.nih.gov/pubmed/32814113
http://dx.doi.org/10.1053/j.gastro.2020.08.017

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