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Evolution of tumor cells during AsiDNA treatment results in energy exhaustion, decrease in responsiveness to signal, and higher sensitivity to the drug

It is increasingly suggested that ecological and evolutionary sciences could inspire novel therapies against cancer but medical evidence of this remains scarce at the moment. The Achilles heel of conventional and targeted anticancer treatments is intrinsic or acquired resistance following Darwinian...

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Detalles Bibliográficos
Autores principales: Girard, Pierre‐Marie, Berthault, Nathalie, Kozlac, Maria, Ferreira, Sofia, Jdey, Wael, Bhaskara, Srividya, Alekseev, Sergey, Thomas, Frederic, Dutreix, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428804/
https://www.ncbi.nlm.nih.gov/pubmed/32821277
http://dx.doi.org/10.1111/eva.12949