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Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs

OBJECTIVES: Occupational exposure to trichloroethylene (TCE) induces trichloroethylene hypersensitivity syndrome (TCEHS), which causes hypersensitivity dermatitis and hepatitis. However, whether TCE itself or its two metabolites, trichloroethanol (TCEOH) and trichloroacetic acid (TCA), are involved...

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Detalles Bibliográficos
Autores principales: Zhao, Na, Song, Xiangrong, Naito, Hisao, Li, Hongling, Huang, Yongshun, Liu, Lili, Lu, Fengrong, Cai, Tingfeng, Ito, Yuki, Kamijima, Michihiro, Huang, Hanlin, Nakajima, Tamie, Wang, Hailan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428806/
https://www.ncbi.nlm.nih.gov/pubmed/32799435
http://dx.doi.org/10.1002/1348-9585.12142