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When, why and how tumour clonal diversity predicts survival

The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not well understood. Here, we employ a spatial computational model...

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Detalles Bibliográficos
Autores principales: Noble, Robert, Burley, John T., Le Sueur, Cécile, Hochberg, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428820/
https://www.ncbi.nlm.nih.gov/pubmed/32821272
http://dx.doi.org/10.1111/eva.13057