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Microarray Normalization Revisited for Reproducible Breast Cancer Biomarkers

Precision medicine for breast cancer relies on biomarkers to select therapies. However, the reliability of biomarkers drawn from gene expression arrays has been questioned and calls for reassessment, in particular for large datasets. We revisit widely used data-normalization procedures and evaluate...

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Detalles Bibliográficos
Autores principales: Kenn, Michael, Cacsire Castillo-Tong, Dan, Singer, Christian F., Cibena, Michael, Kölbl, Heinz, Schreiner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428878/
https://www.ncbi.nlm.nih.gov/pubmed/32832541
http://dx.doi.org/10.1155/2020/1363827