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Microarray Normalization Revisited for Reproducible Breast Cancer Biomarkers
Precision medicine for breast cancer relies on biomarkers to select therapies. However, the reliability of biomarkers drawn from gene expression arrays has been questioned and calls for reassessment, in particular for large datasets. We revisit widely used data-normalization procedures and evaluate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428878/ https://www.ncbi.nlm.nih.gov/pubmed/32832541 http://dx.doi.org/10.1155/2020/1363827 |