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In Vivo Imaging of Hypoxia and Neoangiogenesis in Experimental Syngeneic Hepatocellular Carcinoma Tumor Model Using Positron Emission Tomography
INTRODUCTION: Hypoxia-induced α(ν)β(3) integrin and aminopeptidase N (APN/CD13) receptor expression play an important role in tumor neoangiogenesis. APN/CD13-specific (68)Ga-NOTA-c(NGR), α(ν)β(3) integrin-specific (68)Ga-NODAGA-[c(RGD)](2), and hypoxia-specific (68)Ga-DOTA-nitroimidazole enable the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428931/ https://www.ncbi.nlm.nih.gov/pubmed/32832549 http://dx.doi.org/10.1155/2020/4952372 |