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In Vivo Imaging of Hypoxia and Neoangiogenesis in Experimental Syngeneic Hepatocellular Carcinoma Tumor Model Using Positron Emission Tomography

INTRODUCTION: Hypoxia-induced α(ν)β(3) integrin and aminopeptidase N (APN/CD13) receptor expression play an important role in tumor neoangiogenesis. APN/CD13-specific (68)Ga-NOTA-c(NGR), α(ν)β(3) integrin-specific (68)Ga-NODAGA-[c(RGD)](2), and hypoxia-specific (68)Ga-DOTA-nitroimidazole enable the...

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Detalles Bibliográficos
Autores principales: Kis, Adrienn, Szabó, Judit P., Dénes, Noémi, Vágner, Adrienn, Nagy, Gábor, Garai, Ildikó, Fekete, Anikó, Szikra, Dezső, Hajdu, István, Matolay, Orsolya, Méhes, Gábor, Mező, Gábor, Kertész, István, Trencsényi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428931/
https://www.ncbi.nlm.nih.gov/pubmed/32832549
http://dx.doi.org/10.1155/2020/4952372