Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS

A sensitive and reliable ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed for the simultaneous determination of parecoxib and its metabolite valdecoxib in beagles. The effects of dexmedetomidine on the pharmacokinetics of parecoxib and valdecoxib in b...

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Detalles Bibliográficos
Autores principales: Hu, Jie, Lv, Bing-feng, Guo, Wen-jing, Wang, Bo-wen, Miao, Di, Qiu, Xiang-jun, Chen, Xing-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428950/
https://www.ncbi.nlm.nih.gov/pubmed/32832543
http://dx.doi.org/10.1155/2020/1563874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428950/
https://www.ncbi.nlm.nih.gov/pubmed/32832543
http://dx.doi.org/10.1155/2020/1563874

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