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Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS

A sensitive and reliable ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed for the simultaneous determination of parecoxib and its metabolite valdecoxib in beagles. The effects of dexmedetomidine on the pharmacokinetics of parecoxib and valdecoxib in b...

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Detalles Bibliográficos
Autores principales:	Hu, Jie, Lv, Bing-feng, Guo, Wen-jing, Wang, Bo-wen, Miao, Di, Qiu, Xiang-jun, Chen, Xing-peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428950/ https://www.ncbi.nlm.nih.gov/pubmed/32832543 http://dx.doi.org/10.1155/2020/1563874

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