Cargando…
Nck1, But Not Nck2, Mediates Disturbed Flow‐Induced p21‐Activated Kinase Activation and Endothelial Permeability
BACKGROUND: Alteration in hemodynamic shear stress at atheroprone sites promotes endothelial paracellular pore formation and permeability. The molecular mechanism remains unknown. METHODS AND RESULTS: We show that Nck (noncatalytic region of tyrosine kinase) deletion significantly ameliorates distur...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428973/ https://www.ncbi.nlm.nih.gov/pubmed/32468886 http://dx.doi.org/10.1161/JAHA.120.016099 |