DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies

Deep mutational scanning (DMS) enables multiplexed measurement of the effects of thousands of variants of proteins, RNAs, and regulatory elements. Here, we present a customizable pipeline, DiMSum, that represents an end-to-end solution for obtaining variant fitness and error estimates from raw seque...

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Detalles Bibliográficos
Autores principales: Faure, Andre J., Schmiedel, Jörn M., Baeza-Centurion, Pablo, Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429474/
https://www.ncbi.nlm.nih.gov/pubmed/32799905
http://dx.doi.org/10.1186/s13059-020-02091-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429474/
https://www.ncbi.nlm.nih.gov/pubmed/32799905
http://dx.doi.org/10.1186/s13059-020-02091-3

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