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Ethaninidothioic acid (R5421) is not a selective inhibitor of platelet phospholipid scramblase activity

BACKGROUND AND PURPOSE: Ethaninidothioic acid (R5421) has been used as a scramblase inhibitor to determine the role of phospholipid scrambling across a range of systems including platelet procoagulant activity. The selectivity of R5421 has not been thoroughly studied. Here, we characterised the effe...

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Detalles Bibliográficos
Autores principales: Millington‐Burgess, Sarah Louise, Bonna, Arkadiusz M., Rahman, Taufiq, Harper, Matthew Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429475/
https://www.ncbi.nlm.nih.gov/pubmed/32496597
http://dx.doi.org/10.1111/bph.15152