DAXX-inducing phytoestrogens inhibit ER+ tumor initiating cells and delay tumor development

Recurrence of estrogen receptor (ER)-positive breast tumors despite curative-intent adjuvant therapy is thought to be due to enrichment of tumor initiating cells (TIC) during endocrine therapy (ET). Recently, it was identified that by antagonizing the ER, ET promotes rapid degradation of the death-a...

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Detalles Bibliográficos
Autores principales: Peiffer, Daniel S., Ma, Emily, Wyatt, Debra, Albain, Kathy S., Osipo, Clodia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429502/
https://www.ncbi.nlm.nih.gov/pubmed/32864429
http://dx.doi.org/10.1038/s41523-020-00178-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429502/
https://www.ncbi.nlm.nih.gov/pubmed/32864429
http://dx.doi.org/10.1038/s41523-020-00178-5

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