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DAXX-inducing phytoestrogens inhibit ER+ tumor initiating cells and delay tumor development
Recurrence of estrogen receptor (ER)-positive breast tumors despite curative-intent adjuvant therapy is thought to be due to enrichment of tumor initiating cells (TIC) during endocrine therapy (ET). Recently, it was identified that by antagonizing the ER, ET promotes rapid degradation of the death-a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429502/ https://www.ncbi.nlm.nih.gov/pubmed/32864429 http://dx.doi.org/10.1038/s41523-020-00178-5 |