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Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype

Large-scale genetic aberrations that underpin prostate cancer development and progression, such as copy-number alterations (CNAs), have been described but the consequences of specific changes in many identified loci is limited. Germline SNPs in the 3q26.31 locus are associated with aggressive prosta...

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Detalles Bibliográficos
Autores principales: Simpson, Benjamin S., Camacho, Niedzica, Luxton, Hayley J., Pye, Hayley, Finn, Ron, Heavey, Susan, Pitt, Jason, Moore, Caroline M., Whitaker, Hayley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429505/
https://www.ncbi.nlm.nih.gov/pubmed/32796921
http://dx.doi.org/10.1038/s42003-020-01175-x