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TMEM175 mediates Lysosomal function and participates in neuronal injury induced by cerebral ischemia-reperfusion

As the main organelles for the clearance of damaged proteins and damaged organelles, the function of lysosomes is crucial for maintaining the intracellular homeostasis of long-lived neurons. A stable acidic environment is essential for lysosomes to perform their functions. TMEM175 has been identifie...

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Detalles Bibliográficos
Autores principales: Zhang, Mengling, Lu, Haifeng, Xie, Xueshun, Shen, Haitao, Li, Xiang, Zhang, Yunhai, Wu, Jiang, Ni, Jianqiang, Li, Haiying, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429711/
https://www.ncbi.nlm.nih.gov/pubmed/32799888
http://dx.doi.org/10.1186/s13041-020-00651-z