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Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes
The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically regulated by several environmental cues, including amino aci...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429791/ https://www.ncbi.nlm.nih.gov/pubmed/32799865 http://dx.doi.org/10.1186/s12929-020-00679-2 |