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Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes

The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically regulated by several environmental cues, including amino aci...

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Detalles Bibliográficos
Autores principales: Takahara, Terunao, Amemiya, Yuna, Sugiyama, Risa, Maki, Masatoshi, Shibata, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429791/
https://www.ncbi.nlm.nih.gov/pubmed/32799865
http://dx.doi.org/10.1186/s12929-020-00679-2