Cargando…
Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes
The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically regulated by several environmental cues, including amino aci...
Autores principales: | Takahara, Terunao, Amemiya, Yuna, Sugiyama, Risa, Maki, Masatoshi, Shibata, Hideki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429791/ https://www.ncbi.nlm.nih.gov/pubmed/32799865 http://dx.doi.org/10.1186/s12929-020-00679-2 |
Ejemplares similares
-
Amino Acid-Mediated Intracellular Ca(2+) Rise Modulates mTORC1 by Regulating the TSC2-Rheb Axis through Ca(2+)/Calmodulin
por: Amemiya, Yuna, et al.
Publicado: (2021) -
New Insights into the Regulation of mTOR Signaling via Ca(2+)-Binding Proteins
por: Amemiya, Yuna, et al.
Publicado: (2023) -
Multifaceted Roles of ALG-2 in Ca(2+)-Regulated Membrane Trafficking
por: Maki, Masatoshi, et al.
Publicado: (2016) -
Amino acid metabolites, mTORC1 and aging
por: Antikainen, Henri, et al.
Publicado: (2017) -
mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)