N-glycolyl chondroitin synthesis using metabolically engineered E. coli

N-glycolyl chondroitin (Gc-CN) is a metabolite of N-glycolylneuraminic acid (Neu5Gc), a sialic acid that is commonly found in mammals, but not humans. Humans can incorporate exogenous Neu5Gc into their tissues from eating red meat. Neu5Gc cannot be biosynthesized by humans due to an evolutionary mut...

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Detalles Bibliográficos
Autores principales: Awofiranye, Adeola E., Baytas, Sultan N., Xia, Ke, Badri, Abinaya, He, Wenqin, Varki, Ajit, Koffas, Mattheos, Linhardt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429809/
https://www.ncbi.nlm.nih.gov/pubmed/32803432
http://dx.doi.org/10.1186/s13568-020-01084-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429809/
https://www.ncbi.nlm.nih.gov/pubmed/32803432
http://dx.doi.org/10.1186/s13568-020-01084-6

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