Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse model

Biodegradable materials, including the widely used poly (lactic-co-glycolic acid) (PLGA) nanoparticles contained in slow-release drug formulations, scaffolds and implants, are ubiquitous in modern biomedicine and are considered inert or capable of being metabolized through intermediates such as lact...

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Detalles Bibliográficos
Autores principales: Chaplin, Alice, Gao, Huiyun, Asase, Courteney, Rengasamy, Palanivel, Park, Bongsoo, Skander, Danielle, Bebek, Gürkan, Rajagopalan, Sanjay, Maiseyeu, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429827/
https://www.ncbi.nlm.nih.gov/pubmed/32796856
http://dx.doi.org/10.1038/s41598-020-69745-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429827/
https://www.ncbi.nlm.nih.gov/pubmed/32796856
http://dx.doi.org/10.1038/s41598-020-69745-x

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