HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53

E6 oncoprotein derived from high-risk human papillomavirus (HPV) drives the development of cervical cancer through p53 degradation. Because cervical cancer therapies to inactivate HPV or E6 protein are not available, alternative strategies are required. Here, we show that HPV-mediated nuclear export...

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Detalles Bibliográficos
Autores principales: Yi, Sang Ah, Lee, Dong Hoon, Kim, Go Woon, Ryu, Hyun-Wook, Park, Jong Woo, Lee, Jaecheol, Han, Jihoon, Park, Jee Hun, Oh, Hwamok, Lee, Jieun, Choi, Junjeong, Kim, Hyun-Soo, Kang, Hyeok Gu, Kim, Da-Hyun, Chun, Kyung-Hee, You, Jueng Soo, Han, Jeung-Whan, Kwon, So Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429875/
https://www.ncbi.nlm.nih.gov/pubmed/32203172
http://dx.doi.org/10.1038/s41418-020-0520-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429875/
https://www.ncbi.nlm.nih.gov/pubmed/32203172
http://dx.doi.org/10.1038/s41418-020-0520-5

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