LncRNA KCNQ1OT1 sponges miR-15a to promote immune evasion and malignant progression of prostate cancer via up-regulating PD-L1

BACKGROUND: We focused on the KCNQ1OT1/miR-15a/PD-L1 axis and explored its significance in regulating immune evasion and malignant behaviors of prostate cancer (PC) cells. METHODS: The expression levels of KCNQ1OT1, miR-15a, PD-L1, and CD8 in cells or tissues were examined by RT-qPCR, western blot o...

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Detalles Bibliográficos
Autores principales: Chen, Qi-Hua, Li, Bo, Liu, De-Guo, Zhang, Biao, Yang, Xian, Tu, Ya-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429893/
https://www.ncbi.nlm.nih.gov/pubmed/32821247
http://dx.doi.org/10.1186/s12935-020-01481-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429893/
https://www.ncbi.nlm.nih.gov/pubmed/32821247
http://dx.doi.org/10.1186/s12935-020-01481-8

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