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Severe ineffective erythropoiesis discriminates prognosis in myelodysplastic syndromes: analysis based on 776 patients from a single centre

The underlying mechanisms and clinical significance of ineffective erythropoiesis in myelodysplastic syndromes (MDS) remain to be fully defined. We conducted the ex vivo erythroid differentiation of megakaryocytic-erythroid progenitors (MEPs) from MDS patients and discovered that patient-derived ery...

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Detalles Bibliográficos
Autores principales: Huang, Huijun, Xu, Changlu, Gao, Jie, Li, Bing, Qin, Tiejun, Xu, Zefeng, Ren, Sirui, Zhang, Yudi, Jiao, Meng, Qu, Shiqiang, Pan, Lijuan, Hu, Naibo, Liu, Jinqin, Cai, Wenyu, Zhang, Yingnan, Wu, Dan, Zhang, Peihong, Gale, Robert Peter, Huang, Gang, Zhou, Jiaxi, Shi, Lihong, Xiao, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429953/
https://www.ncbi.nlm.nih.gov/pubmed/32801296
http://dx.doi.org/10.1038/s41408-020-00349-4