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Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Overexpressed EphB4 conduce to tumor development and is regarded as a potential anticancer target. Homoharringtonine (HHT) has been approved for hematologic malignancies treatment, but its effect on hepatocellular carcinoma (HCC) has not been studied. This study elucidated HHT could restrain the pro...

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Detalles Bibliográficos
Autores principales: Zhu, Man, Gong, Zhengyan, Wu, Qing, Su, Qi, Yang, Tianfeng, Yu, Runze, Xu, Rui, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429962/
https://www.ncbi.nlm.nih.gov/pubmed/32801343
http://dx.doi.org/10.1038/s41419-020-02902-2