A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells

BACKGROUND: Mesenchymal stem cells (MSCs) have been widely used for stem cell therapy, and serial passage of stem cells is often required to obtain sufficient cell numbers for practical applications in regenerative medicine. A long-term serial cell expansion can potentially induce replicative senesc...

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Detalles Bibliográficos
Autores principales: Choi, Da Hyeon, Oh, Se-Young, Choi, Ju Kwang, Lee, Kyeong Eun, Lee, Ju Yeon, Park, Yoon Jeong, Jo, Inho, Park, Yoon Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027/
https://www.ncbi.nlm.nih.gov/pubmed/32807231
http://dx.doi.org/10.1186/s13287-020-01860-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027/
https://www.ncbi.nlm.nih.gov/pubmed/32807231
http://dx.doi.org/10.1186/s13287-020-01860-y

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