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Detection of ctDNA in plasma of patients with clinically localised prostate cancer is associated with rapid disease progression

BACKGROUND: DNA originating from degenerate tumour cells can be detected in the circulation in many tumour types, where it can be used as a marker of disease burden as well as to monitor treatment response. Although circulating tumour DNA (ctDNA) measurement has prognostic/predictive value in metast...

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Detalles Bibliográficos
Autores principales: Lau, Edmund, McCoy, Patrick, Reeves, Fairleigh, Chow, Ken, Clarkson, Michael, Kwan, Edmond M., Packwood, Kate, Northen, Helen, He, Miao, Kingsbury, Zoya, Mangiola, Stefano, Kerger, Michael, Furrer, Marc A., Crowe, Helen, Costello, Anthony J., McBride, David J., Ross, Mark T., Pope, Bernard, Hovens, Christopher M., Corcoran, Niall M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430029/
https://www.ncbi.nlm.nih.gov/pubmed/32807235
http://dx.doi.org/10.1186/s13073-020-00770-1