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Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes

INTRODUCTION: Local T-cell immunity is recognized for its contribution to the evolution and therapy response of various carcinomas. Here, we investigated characteristics of tumor-infiltrating lymphocytes (TILs), as well as T-cell evasive mechanisms in different soft tissue sarcoma (STS) subtypes. ME...

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Detalles Bibliográficos
Autores principales: Klaver, Yarne, Rijnders, Maud, Oostvogels, Astrid, Wijers, Rebecca, Smid, Marcel, Grünhagen, Dirk, Verhoef, Cornelis, Sleijfer, Stefan, Lamers, Cor, Debets, Reno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430493/
https://www.ncbi.nlm.nih.gov/pubmed/32792357
http://dx.doi.org/10.1136/jitc-2019-000271