Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations

We studied the activity of a range of weakly basic and moderately lipophilic drugs against SARS CoV2 in Vero E6 cells, using Vero E6 survival, qPCR of viral genome and plaque forming assays. No clear relationship between their weakly basic and hydrophobic nature upon their activity was observed. How...

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Detalles Bibliográficos
Autores principales: Bradfute, Steven B, Ye, Chunyan, Clarke, Elizabeth C, Kumar, Suresh, Timmins, Graham S, Deretic, Vojo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430564/
https://www.ncbi.nlm.nih.gov/pubmed/32817934
http://dx.doi.org/10.1101/2020.08.11.245100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430564/
https://www.ncbi.nlm.nih.gov/pubmed/32817934
http://dx.doi.org/10.1101/2020.08.11.245100

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