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Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations
We studied the activity of a range of weakly basic and moderately lipophilic drugs against SARS CoV2 in Vero E6 cells, using Vero E6 survival, qPCR of viral genome and plaque forming assays. No clear relationship between their weakly basic and hydrophobic nature upon their activity was observed. How...
Autores principales: | Bradfute, Steven B, Ye, Chunyan, Clarke, Elizabeth C, Kumar, Suresh, Timmins, Graham S, Deretic, Vojo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430564/ https://www.ncbi.nlm.nih.gov/pubmed/32817934 http://dx.doi.org/10.1101/2020.08.11.245100 |
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