A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation

The catalytic activity of human AURORA-A kinase (AURKA) regulates mitotic progression, and its frequent overexpression in major forms of epithelial cancer is associated with aneuploidy and carcinogenesis. Here, we report an unexpected, kinase-independent function for AURKA in DNA replication initiat...

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Detalles Bibliográficos
Autores principales: Guarino Almeida, Estrella, Renaudin, Xavier, Venkitaraman, Ashok R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430631/
https://www.ncbi.nlm.nih.gov/pubmed/32652013
http://dx.doi.org/10.1093/nar/gkaa570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430631/
https://www.ncbi.nlm.nih.gov/pubmed/32652013
http://dx.doi.org/10.1093/nar/gkaa570

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