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Eukaryotic life without tQ(CUG): the role of Elongator-dependent tRNA modifications in Dictyostelium discoideum

In the Elongator-dependent modification pathway, chemical modifications are introduced at the wobble uridines at position 34 in transfer RNAs (tRNAs), which serve to optimize codon translation rates. Here, we show that this three-step modification pathway exists in Dictyostelium discoideum, model of...

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Detalles Bibliográficos
Autores principales: Schäck, Manfred A, Jablonski, Kim Philipp, Gräf, Stefan, Klassen, Roland, Schaffrath, Raffael, Kellner, Stefanie, Hammann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430636/
https://www.ncbi.nlm.nih.gov/pubmed/32609816
http://dx.doi.org/10.1093/nar/gkaa560