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Augmented base pairing networks encode RNA-small molecule binding preferences

RNA-small molecule binding is a key regulatory mechanism which can stabilize 3D structures and activate molecular functions. The discovery of RNA-targeting compounds is thus a current topic of interest for novel therapies. Our work is a first attempt at bringing the scalability and generalization ab...

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Detalles Bibliográficos
Autores principales: Oliver, Carlos, Mallet, Vincent, Gendron, Roman Sarrazin, Reinharz, Vladimir, Hamilton, William L, Moitessier, Nicolas, Waldispühl, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430648/
https://www.ncbi.nlm.nih.gov/pubmed/32652015
http://dx.doi.org/10.1093/nar/gkaa583