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Augmented base pairing networks encode RNA-small molecule binding preferences
RNA-small molecule binding is a key regulatory mechanism which can stabilize 3D structures and activate molecular functions. The discovery of RNA-targeting compounds is thus a current topic of interest for novel therapies. Our work is a first attempt at bringing the scalability and generalization ab...
Autores principales: | Oliver, Carlos, Mallet, Vincent, Gendron, Roman Sarrazin, Reinharz, Vladimir, Hamilton, William L, Moitessier, Nicolas, Waldispühl, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430648/ https://www.ncbi.nlm.nih.gov/pubmed/32652015 http://dx.doi.org/10.1093/nar/gkaa583 |
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