Bulk and single-molecule analysis of a bacterial DNA2-like helicase–nuclease reveals a single-stranded DNA looping motor

DNA2 is an essential enzyme involved in DNA replication and repair in eukaryotes. In a search for homologues of this protein, we identified and characterised Geobacillus stearothermophilus Bad, a bacterial DNA helicase–nuclease with similarity to human DNA2. We show that Bad contains an Fe-S cluster...

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Detalles Bibliográficos
Autores principales: Wilkinson, Oliver J, Carrasco, Carolina, Aicart-Ramos, Clara, Moreno-Herrero, Fernando, Dillingham, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430649/
https://www.ncbi.nlm.nih.gov/pubmed/32621607
http://dx.doi.org/10.1093/nar/gkaa562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430649/
https://www.ncbi.nlm.nih.gov/pubmed/32621607
http://dx.doi.org/10.1093/nar/gkaa562

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