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Highly specific, multiplexed isothermal pathogen detection with fluorescent aptamer readout

Isothermal, cell-free, synthetic biology-based approaches to pathogen detection leverage the power of tools available in biological systems, such as highly active polymerases compatible with lyophilization, without the complexity inherent to live-cell systems, of which nucleic acid sequence based am...

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Detalles Bibliográficos
Autores principales: Aufdembrink, Lauren M., Khan, Pavana, Gaut, Nathaniel J., Adamala, Katarzyna P., Engelhart, Aaron E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430665/
https://www.ncbi.nlm.nih.gov/pubmed/32482894
http://dx.doi.org/10.1261/rna.075192.120