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A combinatorially regulated RNA splicing signature predicts breast cancer EMT states and patient survival

During breast cancer metastasis, the developmental process epithelial–mesenchymal transition (EMT) is abnormally activated. Transcriptional regulatory networks controlling EMT are well-studied; however, alternative RNA splicing also plays a critical regulatory role during this process. A comprehensi...

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Detalles Bibliográficos
Autores principales: Qiu, Yushan, Lyu, Jingyi, Dunlap, Mikayla, Harvey, Samuel E., Cheng, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430667/
https://www.ncbi.nlm.nih.gov/pubmed/32467311
http://dx.doi.org/10.1261/rna.074187.119