Cargando…

Parallel poly(A) homo- and hetero-duplex formation detection with an adapted DNA nanoswitch technique

Polyriboadenylic [poly(rA)] strands of sufficient length form parallel double helices in acidic and/or ammonium-containing conditions. Poly(rA) duplexes in acidic conditions are held together by A(+)–A(+) base-pairing also involving base interactions with the phosphate backbone. Traditional UV-melti...

Descripción completa

Detalles Bibliográficos
Autores principales: Pickard, Martha Anne G., Brylow, Karl B., Cisco, Lily A., Anecelle, Matthew R., Pershun, Mackenzie L., Chandrasekaran, Arun Richard, Halvorsen, Ken, Gleghorn, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430668/
https://www.ncbi.nlm.nih.gov/pubmed/32414856
http://dx.doi.org/10.1261/rna.075408.120