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Parallel poly(A) homo- and hetero-duplex formation detection with an adapted DNA nanoswitch technique
Polyriboadenylic [poly(rA)] strands of sufficient length form parallel double helices in acidic and/or ammonium-containing conditions. Poly(rA) duplexes in acidic conditions are held together by A(+)–A(+) base-pairing also involving base interactions with the phosphate backbone. Traditional UV-melti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430668/ https://www.ncbi.nlm.nih.gov/pubmed/32414856 http://dx.doi.org/10.1261/rna.075408.120 |