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Pseudouridine-mediated stop codon readthrough in S. cerevisiae is sequence context–independent
We have previously shown that when the uridine of a stop codon (UAA, UAG, or UGA) is pseudouridylated, the ribosome reads through the modified stop codon. However, it is not clear as to whether or not the pseudouridine (Ψ)-mediated readthrough is dependent on the sequence context of mRNA. Here, we u...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430670/ https://www.ncbi.nlm.nih.gov/pubmed/32434780 http://dx.doi.org/10.1261/rna.076042.120 |