Chemical crosslinking enhances RNA immunoprecipitation for efficient identification of binding sites of proteins that photo-crosslink poorly with RNA

In eukaryotic cells, proteins that associate with RNA regulate its activity to control cellular function. To fully illuminate the basis of RNA function, it is essential to identify such RNA-associated proteins, their mode of action on RNA, and their preferred RNA targets and binding sites. By analyz...

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Detalles Bibliográficos
Autores principales: Patton, Robert D., Sanjeev, Manu, Woodward, Lauren A., Mabin, Justin W., Bundschuh, Ralf, Singh, Guramrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430673/
https://www.ncbi.nlm.nih.gov/pubmed/32467309
http://dx.doi.org/10.1261/rna.074856.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430673/
https://www.ncbi.nlm.nih.gov/pubmed/32467309
http://dx.doi.org/10.1261/rna.074856.120

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